Oligomer-Targeting Prevention of Neurodegenerative Dementia by Intranasal Rifampicin and Resveratrol Combination – A Preclinical Study in Model Mice

Amyloidogenic protein oligomers are thought to play an important role in the pathogenesis of neurodegenerative dementia, including Alzheimer’s disease, frontotemporal dementia, and dementia with Lewy bodies. Previously we demonstrated that oral or intranasal rifampicin improved the cognition of APP-...

Descripción completa

Detalles Bibliográficos
Autores principales: Umeda, Tomohiro, Sakai, Ayumi, Shigemori, Keiko, Yokota, Ayumi, Kumagai, Toru, Tomiyama, Takami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710719/
https://www.ncbi.nlm.nih.gov/pubmed/34966254
http://dx.doi.org/10.3389/fnins.2021.763476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710719/
https://www.ncbi.nlm.nih.gov/pubmed/34966254
http://dx.doi.org/10.3389/fnins.2021.763476

Ejemplares similares