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Sirtuin 5 is Dispensable for CD8(+) T Cell Effector and Memory Differentiation

CD8(+) T cell effector and memory differentiation is tightly controlled at multiple levels including transcriptional, metabolic, and epigenetic regulation. Sirtuin 5 (SIRT5) is a protein deacetylase mainly located at mitochondria, but it remains unclear whether SIRT5 plays key roles in regulating CD...

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Detalles Bibliográficos
Autores principales: Duan, Qianqian, Ding, Jiying, Li, Fangfang, Liu, Xiaowei, Zhao, Yunan, Yu, Hongxiu, Liu, Yong, Zhang, Lianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710726/
https://www.ncbi.nlm.nih.gov/pubmed/34966740
http://dx.doi.org/10.3389/fcell.2021.761193