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Protocol for the Metformin Aneurysm Trial (MAT): a placebo-controlled randomised trial testing whether metformin reduces the risk of serious complications of abdominal aortic aneurysm

BACKGROUND: Multiple observational studies have associated metformin prescription with reduced progression of abdominal aortic aneurysm (AAA). The Metformin Aneurysm Trial (MAT) will test whether metformin reduces the risk of AAA rupture-related mortality or requirement for AAA surgery (AAA events)...

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Detalles Bibliográficos
Autores principales: Golledge, Jonathan, Arnott, Clare, Moxon, Joseph, Monaghan, Helen, Norman, Richard, Morris, Dylan, Li, Qiang, Jones, Greg, Roake, Justin, Bown, Matt, Neal, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710921/
https://www.ncbi.nlm.nih.gov/pubmed/34961561
http://dx.doi.org/10.1186/s13063-021-05915-0