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Secretome effect of adipose tissue-derived stem cells cultured two-dimensionally and three-dimensionally in mice with streptozocin induced type 1 diabetes

AIMS: To analyze therapeutic potential of the conditioned medium from adipose tissue-derived stem cells (ASC) cultivated in 2D (CM-2D) and 3D (CM-3D) models, in mice with Type 1 diabetes (T1D) induced by streptozotocin. MAIN METHODS: Viability andCD105 expression of 2D and 3D ASC were analyzed by fl...

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Detalles Bibliográficos
Autores principales: Dias, Isabelle, Pinheiro, Daphne, Ribeiro Silva, Karina, Stumbo, Ana Carolina, Thole, Alessandra, Cortez, Erika, de Carvalho, Laís, Carvalho, Simone Nunes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710992/
https://www.ncbi.nlm.nih.gov/pubmed/34988430
http://dx.doi.org/10.1016/j.crphar.2021.100069