The Effect of CHIR 99021, a Glycogen Synthase Kinase-3β Inhibitor, on Transforming Growth Factor β-Induced Tenon Fibrosis

PURPOSE: This study investigated the effect of glycogen synthase kinase-3β (GSK-3β) inhibition on the fibrosis of human Tenon's fibroblasts (HTFs) induced by transforming growth factor-β (TGF-β). METHODS: Quantitative real-time PCR and Western blot analyses were performed to determine the expre...

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Detalles Bibliográficos
Autores principales: Lee, Sang Yeop, Chae, Min Kyoung, Yoon, Jin Sook, Kim, Chan Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Glaucoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711002/
https://www.ncbi.nlm.nih.gov/pubmed/34940783
http://dx.doi.org/10.1167/iovs.62.15.25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711002/
https://www.ncbi.nlm.nih.gov/pubmed/34940783
http://dx.doi.org/10.1167/iovs.62.15.25

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