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The Effect of CHIR 99021, a Glycogen Synthase Kinase-3β Inhibitor, on Transforming Growth Factor β-Induced Tenon Fibrosis
PURPOSE: This study investigated the effect of glycogen synthase kinase-3β (GSK-3β) inhibition on the fibrosis of human Tenon's fibroblasts (HTFs) induced by transforming growth factor-β (TGF-β). METHODS: Quantitative real-time PCR and Western blot analyses were performed to determine the expre...
Autores principales: | Lee, Sang Yeop, Chae, Min Kyoung, Yoon, Jin Sook, Kim, Chan Yun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711002/ https://www.ncbi.nlm.nih.gov/pubmed/34940783 http://dx.doi.org/10.1167/iovs.62.15.25 |
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