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AIM2 inhibits the proliferation, invasion and migration, and promotes the apoptosis of osteosarcoma cells by inactivating the PI3K/AKT/mTOR signaling pathway

Osteosarcoma is a primary bone tumor that mainly occurs in children and adolescents. Absent in melanoma 2 (AIM2) has been demonstrated to be involved in regulating the occurrence and development of cancer, exerting oncogenic and pro-cancer effects; however, its role in osteosarcoma is poorly underst...

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Detalles Bibliográficos
Autores principales: Zheng, Jianping, Liu, Changhao, Shi, Jiandang, Wen, Kun, Wang, Xiangxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711022/
https://www.ncbi.nlm.nih.gov/pubmed/34913077
http://dx.doi.org/10.3892/mmr.2021.12569