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AIM2 inhibits the proliferation, invasion and migration, and promotes the apoptosis of osteosarcoma cells by inactivating the PI3K/AKT/mTOR signaling pathway
Osteosarcoma is a primary bone tumor that mainly occurs in children and adolescents. Absent in melanoma 2 (AIM2) has been demonstrated to be involved in regulating the occurrence and development of cancer, exerting oncogenic and pro-cancer effects; however, its role in osteosarcoma is poorly underst...
Autores principales: | Zheng, Jianping, Liu, Changhao, Shi, Jiandang, Wen, Kun, Wang, Xiangxin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711022/ https://www.ncbi.nlm.nih.gov/pubmed/34913077 http://dx.doi.org/10.3892/mmr.2021.12569 |
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