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Bhlhe40: Gatekeeper of the GC

The generation of high-affinity antibodies in the germinal center (GC) requires interplay between GC B cells and T follicular helper cells. Rauschmeier et al. (2021. J. Exp. Med. https://doi.org/10.1084/jem.20211406) report that Bhlhe40 restrains GC output through distinct regulatory roles in both a...

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Detalles Bibliográficos
Autores principales: Nutt, Stephen L., Tellier, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711044/
https://www.ncbi.nlm.nih.gov/pubmed/34940789
http://dx.doi.org/10.1084/jem.20212333