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Changes in chromatin accessibility landscape and histone H3 core acetylation during valproic acid-induced differentiation of embryonic stem cells

Directed differentiation of mouse embryonic stem cells (mESCs) or induced pluripotent stem cells (iPSCs) provides powerful models to dissect the molecular mechanisms leading to the formation of specific cell lineages. Treatment with histone deacetylase inhibitors can significantly enhance the effici...

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Detalles Bibliográficos
Autores principales: Baumann, Claudia, Zhang, Xiangyu, Zhu, Ling, Fan, Yuhong, De La Fuente, Rabindranath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711205/
https://www.ncbi.nlm.nih.gov/pubmed/34955095
http://dx.doi.org/10.1186/s13072-021-00432-5