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Herceptin induces ferroptosis and mitochondrial dysfunction in H9c2 cells
Ferroptosis has been previously implicated in the pathological progression of cardiomyopathy. Herceptin (trastuzumab), which targets HER2, is commonly applied for the treatment of HER2(+) breast cancer. However, its clinical use is limited by its cardiotoxicity. Therefore, the present study aimed to...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711589/ https://www.ncbi.nlm.nih.gov/pubmed/34935058 http://dx.doi.org/10.3892/ijmm.2021.5072 |