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Nonsense-mediated mRNA decay uses complementary mechanisms to suppress mRNA and protein accumulation
Nonsense-mediated mRNA decay (NMD) is an essential, highly conserved quality control pathway that detects and degrades mRNAs containing premature termination codons. Although the essentiality of NMD is frequently ascribed to its prevention of truncated protein accumulation, the extent to which NMD a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Life Science Alliance LLC
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711849/ https://www.ncbi.nlm.nih.gov/pubmed/34880103 http://dx.doi.org/10.26508/lsa.202101217 |