Cargando…

Nonsense-mediated mRNA decay uses complementary mechanisms to suppress mRNA and protein accumulation

Nonsense-mediated mRNA decay (NMD) is an essential, highly conserved quality control pathway that detects and degrades mRNAs containing premature termination codons. Although the essentiality of NMD is frequently ascribed to its prevention of truncated protein accumulation, the extent to which NMD a...

Descripción completa

Detalles Bibliográficos
Autores principales: Udy, Dylan B, Bradley, Robert K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711849/
https://www.ncbi.nlm.nih.gov/pubmed/34880103
http://dx.doi.org/10.26508/lsa.202101217