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GPX4-Regulated Ferroptosis Mediates S100-Induced Experimental Autoimmune Hepatitis Associated with the Nrf2/HO-1 Signaling Pathway

Autoimmune hepatitis (AIH) is an inflammatory autoimmune disease of the liver. Oxidative stress triggered by reactive oxygen radicals is a common pathophysiological basis for the pathogenesis of many liver diseases, and ferroptosis is associated with the toxic accumulation of reactive oxygen species...

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Detalles Bibliográficos
Autores principales: Zhu, Lujian, Chen, Dazhi, Zhu, Yin, Pan, Tongtong, Xia, Dingchao, Cai, Tingchen, Lin, Hongwei, Lin, Jing, Jin, Xiaozhi, Wu, Faling, Yu, Sijie, Zhu, Kailu, Xu, Lanman, Chen, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712167/
https://www.ncbi.nlm.nih.gov/pubmed/34966478
http://dx.doi.org/10.1155/2021/6551069