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Activity of temocillin against third-generation cephalosporin-resistant Escherichia coli and Klebsiella pneumoniae bloodstream isolates from a clinical trial

BACKGROUND: Extended spectrum β-lactamase (ESBL) and AmpC-producing Gram-negative bacilli contribute significantly to the antimicrobial resistance (AMR) burden worldwide. Temocillin is an intravenous semisynthetic antibiotic that is stable to hydrolysis by ESBLs and AmpC. Temocillin may be a treatme...

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Detalles Bibliográficos
Autores principales: Stewart, Adam G, Henderson, Andrew, Bauer, Michelle J, Paterson, David L, Harris, Patrick N A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712245/
https://www.ncbi.nlm.nih.gov/pubmed/34988445
http://dx.doi.org/10.1093/jacamr/dlab192