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Have (R)-[(11)C]PK11195 challengers fulfilled the promise? A scoping review of clinical TSPO PET studies

PURPOSE: The prototypical TSPO radiotracer (R)-[(11)C]PK11195 has been used in humans for more than thirty years to visualize neuroinflammation in several pathologies. Alternative radiotracers have been developed to improve signal-to-noise ratio and started to be tested clinically in 2008. Here we e...

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Detalles Bibliográficos
Autores principales: Chauveau, Fabien, Becker, Guillaume, Boutin, Hervé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712292/
https://www.ncbi.nlm.nih.gov/pubmed/34387719
http://dx.doi.org/10.1007/s00259-021-05425-w