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Radiosynthesis and characterization of [(18)F]BS224: a next-generation TSPO PET ligand insensitive to the rs6971 polymorphism
PURPOSE: Translocator protein 18-kDa (TSPO) positron emission tomography (PET) is a valuable tool to detect neuroinflammed areas in a broad spectrum of neurodegenerative diseases. However, the clinical application of second-generation TSPO ligands as biomarkers is limited because of the presence of...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712300/ https://www.ncbi.nlm.nih.gov/pubmed/34783879 http://dx.doi.org/10.1007/s00259-021-05617-4 |