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Radiosynthesis and characterization of [(18)F]BS224: a next-generation TSPO PET ligand insensitive to the rs6971 polymorphism

PURPOSE: Translocator protein 18-kDa (TSPO) positron emission tomography (PET) is a valuable tool to detect neuroinflammed areas in a broad spectrum of neurodegenerative diseases. However, the clinical application of second-generation TSPO ligands as biomarkers is limited because of the presence of...

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Detalles Bibliográficos
Autores principales: Lee, Sang Hee, Denora, Nunzio, Laquintana, Valentino, Mangiatordi, Giuseppe Felice, Lopedota, Angela, Lopalco, Antonio, Cutrignelli, Annalisa, Franco, Massimo, Delre, Pietro, Song, In Ho, Kim, Hye Won, Kim, Su Bin, Park, Hyun Soo, Kim, Kyungmin, Lee, Seok-Yong, Youn, Hyewon, Lee, Byung Chul, Kim, Sang Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712300/
https://www.ncbi.nlm.nih.gov/pubmed/34783879
http://dx.doi.org/10.1007/s00259-021-05617-4