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Radiosynthesis and characterization of [(18)F]BS224: a next-generation TSPO PET ligand insensitive to the rs6971 polymorphism
PURPOSE: Translocator protein 18-kDa (TSPO) positron emission tomography (PET) is a valuable tool to detect neuroinflammed areas in a broad spectrum of neurodegenerative diseases. However, the clinical application of second-generation TSPO ligands as biomarkers is limited because of the presence of...
Autores principales: | Lee, Sang Hee, Denora, Nunzio, Laquintana, Valentino, Mangiatordi, Giuseppe Felice, Lopedota, Angela, Lopalco, Antonio, Cutrignelli, Annalisa, Franco, Massimo, Delre, Pietro, Song, In Ho, Kim, Hye Won, Kim, Su Bin, Park, Hyun Soo, Kim, Kyungmin, Lee, Seok-Yong, Youn, Hyewon, Lee, Byung Chul, Kim, Sang Eun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712300/ https://www.ncbi.nlm.nih.gov/pubmed/34783879 http://dx.doi.org/10.1007/s00259-021-05617-4 |
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