Novel CYP11B-ligand [(123/131)I]IMAZA as promising theranostic tool for adrenocortical tumors: comprehensive preclinical characterization and first clinical experience

PURPOSE: Adrenal tumors represent a diagnostic and therapeutic challenge. Promising results have been obtained through targeting the cytochrome P450 enzymes CYP11B1 and CYP11B2 for molecular imaging, and [(123/131)I]iodometomidate ([(123/131)I]IMTO) has even been successfully introduced as a therano...

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Detalles Bibliográficos
Autores principales: Heinze, Britta, Schirbel, Andreas, Nannen, Lukas, Michelmann, David, Hartrampf, Philipp E., Bluemel, Christina, Schneider, Magdalena, Herrmann, Ken, Haenscheid, Heribert, Fassnacht, Martin, Buck, Andreas K., Hahner, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712301/
https://www.ncbi.nlm.nih.gov/pubmed/34215922
http://dx.doi.org/10.1007/s00259-021-05477-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712301/
https://www.ncbi.nlm.nih.gov/pubmed/34215922
http://dx.doi.org/10.1007/s00259-021-05477-y

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