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Modelling [(18)F]LW223 PET data using simplified imaging protocols for quantification of TSPO expression in the rat heart and brain

PURPOSE: To provide a comprehensive assessment of the novel 18 kDa translocator protein (TSPO) radiotracer, [(18)F]LW223, kinetics in the heart and brain when using a simplified imaging approach. METHODS: Naive adult rats and rats with surgically induced permanent coronary artery ligation received a...

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Detalles Bibliográficos
Autores principales: MacAskill, Mark G., Wimberley, Catriona, Morgan, Timaeus E. F., Alcaide-Corral, Carlos J., Newby, David E., Lucatelli, Christophe, Sutherland, Andrew, Pimlott, Sally L., Tavares, Adriana A. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712302/
https://www.ncbi.nlm.nih.gov/pubmed/34338808
http://dx.doi.org/10.1007/s00259-021-05482-1