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Transition Therapy: Tackling the Ecology of Tumor Phenotypic Plasticity

Phenotypic switching in cancer cells has been found to be present across tumor types. Recent studies on Glioblastoma report a remarkably common architecture of four well-defined phenotypes coexisting within high levels of intra-tumor genetic heterogeneity. Similar dynamics have been shown to occur i...

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Detalles Bibliográficos
Autores principales: Aguadé-Gorgorió, Guim, Kauffman, Stuart, Solé, Ricard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712307/
https://www.ncbi.nlm.nih.gov/pubmed/34958403
http://dx.doi.org/10.1007/s11538-021-00970-9