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Transition Therapy: Tackling the Ecology of Tumor Phenotypic Plasticity
Phenotypic switching in cancer cells has been found to be present across tumor types. Recent studies on Glioblastoma report a remarkably common architecture of four well-defined phenotypes coexisting within high levels of intra-tumor genetic heterogeneity. Similar dynamics have been shown to occur i...
Autores principales: | Aguadé-Gorgorió, Guim, Kauffman, Stuart, Solé, Ricard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712307/ https://www.ncbi.nlm.nih.gov/pubmed/34958403 http://dx.doi.org/10.1007/s11538-021-00970-9 |
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