Cargando…
The Pyruvate Dehydrogenase Complex in Sepsis: Metabolic Regulation and Targeted Therapy
Anaerobic glycolysis is the process by which glucose is broken down into pyruvate and lactate and is the primary metabolic pathway in sepsis. The pyruvate dehydrogenase complex (PDHC) is a multienzyme complex that serves as a critical hub in energy metabolism. Under aerobic conditions, pyruvate tran...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712327/ https://www.ncbi.nlm.nih.gov/pubmed/34970577 http://dx.doi.org/10.3389/fnut.2021.783164 |