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The Pyruvate Dehydrogenase Complex in Sepsis: Metabolic Regulation and Targeted Therapy

Anaerobic glycolysis is the process by which glucose is broken down into pyruvate and lactate and is the primary metabolic pathway in sepsis. The pyruvate dehydrogenase complex (PDHC) is a multienzyme complex that serves as a critical hub in energy metabolism. Under aerobic conditions, pyruvate tran...

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Detalles Bibliográficos
Autores principales:	Zeng, Zhenhua, Huang, Qiaobing, Mao, Liangfeng, Wu, Jie, An, Sheng, Chen, Zhongqing, Zhang, Weijin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Nutrition
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712327/ https://www.ncbi.nlm.nih.gov/pubmed/34970577 http://dx.doi.org/10.3389/fnut.2021.783164

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