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Cryo-EM of CcsBA reveals the basis for cytochrome c biogenesis and heme transport

Although the individual structures and respiratory functions of cytochromes are well studied, the structural basis for their assembly, including transport of heme for attachment, are unknown. We describe cryo-EM structures of CcsBA, a bifunctional heme transporter and cytochrome c synthase. Models b...

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Detalles Bibliográficos
Autores principales: Mendez, Deanna L., Lowder, Ethan P., Tillman, Dustin E., Sutherland, Molly C., Collier, Andrea L., Rau, Michael J., Fitzpatrick, James A.J., Kranz, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712405/
https://www.ncbi.nlm.nih.gov/pubmed/34931065
http://dx.doi.org/10.1038/s41589-021-00935-y