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WAY-100635 Alleviates Corneal Lesions Through 5-HT(1A) Receptor-ROS-Autophagy Axis in Dry Eye

Purpose: To explore whether 5-HT(1A) receptors are involved in the dry eye disease (DED) mouse model and reveal its underlying mechanism. Methods: A C57BL/6J mouse DED model was established via the administration of 0.2% benzalkonium chloride twice a day for 14 days. Corneal fluorescein sodium stain...

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Detalles Bibliográficos
Autores principales: Zhou, Xujiao, Dai, Yiqin, Zhai, Zimeng, Hong, Jiaxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712493/
https://www.ncbi.nlm.nih.gov/pubmed/34970573
http://dx.doi.org/10.3389/fmed.2021.799949