A selective Cu(II) complex with 4-fluorophenoxyacetic acid hydrazide and phenanthroline displays DNA-cleaving and pro-apoptotic properties in cancer cells

The thin line between efficacy and toxicity has challenged cancer therapy. As copper is an essential micronutrient and is important to tumor biology, Cu(II) complexes emerged as an alternative to chemotherapy; however, its biological properties need to be better understood. Thus, we report in vitro...

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Detalles Bibliográficos
Autores principales: Machado, Pedro Henrique Alves, Paixão, Drielly Aparecida, Lino, Ricardo Campos, de Souza, Tiago Rodrigues, de Souza Bontempo, Nayara Júnia, Sousa, Luana Munique, Van Petten de Vasconcelos Azevedo, Fernanda, Orsolin, Priscila Capelari, Lima, Paula Marynella Alves Pereira, Martins, Isabella Castro, da Costa Guerra, Joyce Ferreira, Teixeira, Samuel Cota, Araújo, Thaise Gonçalves, Goulart, Luiz Ricardo, Morelli, Sandra, Guerra, Wendell, de Oliveira Júnior, Robson José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712526/
https://www.ncbi.nlm.nih.gov/pubmed/34961767
http://dx.doi.org/10.1038/s41598-021-03909-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712526/
https://www.ncbi.nlm.nih.gov/pubmed/34961767
http://dx.doi.org/10.1038/s41598-021-03909-1

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