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microRNA-136-5p from bone marrow mesenchymal stem cell-derived exosomes facilitates fracture healing by targeting LRP4 to activate the Wnt/β-catenin pathway

AIMS: Exosomes derived from bone marrow mesenchymal stem cells (BMSCs) have been reported to be a promising cellular therapeutic approach for various human diseases. The current study aimed to investigate the mechanism of BMSC-derived exosomes carrying microRNA (miR)-136-5p in fracture healing. METH...

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Detalles Bibliográficos
Autores principales: Yu, Haichi, Zhang, Jun, Liu, Xiaoning, Li, Yingzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712601/
https://www.ncbi.nlm.nih.gov/pubmed/34847690
http://dx.doi.org/10.1302/2046-3758.1012.BJR-2020-0275.R2