HLA-DRB3/4/5 Matching Improves Outcome of Unrelated Hematopoietic Stem Cell Transplantation

The HLA-DRB3/4/5 loci are closely linked to the HLA-DRB1 gene. Mismatches in these loci occur with a frequency of about 8%–12% in otherwise 10/10 HLA-matched transplant pairs. There is preliminary evidence that these disparities may associate with increased acute graft-versus-host disease (GvHD) rat...

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Detalles Bibliográficos
Autores principales: Tsamadou, Chrysanthi, Engelhardt, Daphne, Platzbecker, Uwe, Sala, Elisa, Valerius, Thomas, Wagner-Drouet, Eva, Wulf, Gerald, Kröger, Nicolaus, Murawski, Niels, Einsele, Hermann, Schaefer-Eckart, Kerstin, Freitag, Sebastian, Casper, Jochen, Kaufmann, Martin, Dürholt, Mareike, Hertenstein, Bernd, Klein, Stefan, Ringhoffer, Mark, Frank, Sandra, Neuchel, Christine, Schrezenmeier, Hubert, Mytilineos, Joannis, Fuerst, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712639/
https://www.ncbi.nlm.nih.gov/pubmed/34970261
http://dx.doi.org/10.3389/fimmu.2021.771449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712639/
https://www.ncbi.nlm.nih.gov/pubmed/34970261
http://dx.doi.org/10.3389/fimmu.2021.771449

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