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Function and Molecular Mechanism of the DNA Damage Response in Immunity and Cancer Immunotherapy
The DNA damage response (DDR) is an organized network of multiple interwoven components evolved to repair damaged DNA and maintain genome fidelity. Conceptually the DDR includes damage sensors, transducer kinases, and effectors to maintain genomic stability and accurate transmission of genetic infor...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712645/ https://www.ncbi.nlm.nih.gov/pubmed/34970273 http://dx.doi.org/10.3389/fimmu.2021.797880 |