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Function and Molecular Mechanism of the DNA Damage Response in Immunity and Cancer Immunotherapy

The DNA damage response (DDR) is an organized network of multiple interwoven components evolved to repair damaged DNA and maintain genome fidelity. Conceptually the DDR includes damage sensors, transducer kinases, and effectors to maintain genomic stability and accurate transmission of genetic infor...

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Detalles Bibliográficos
Autores principales: Ye, Zu, Shi, Yin, Lees-Miller, Susan P., Tainer, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712645/
https://www.ncbi.nlm.nih.gov/pubmed/34970273
http://dx.doi.org/10.3389/fimmu.2021.797880