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Sustained Release of Gas6 via mPEG-PLGA Nanoparticles Enhances the Therapeutic Effects of MERTK Gene Therapy in RCS Rats

Previous researches utilizing MER proto-oncogene tyrosine kinase (MERTK) gene therapy in Royal College of Surgeons (RCS) rats evidenced its effectiveness in treating MERTK-associated retinitis pigmentosa (RP). Specific ligands for receptor tyrosine kinases, such as growth arrest-specific 6 (Gas6), m...

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Detalles Bibliográficos
Autores principales: Wu, Shen, Mao, Yingyan, Liu, Qian, Yan, Xuejing, Zhang, Jingxue, Wang, Ningli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712650/
https://www.ncbi.nlm.nih.gov/pubmed/34970569
http://dx.doi.org/10.3389/fmed.2021.794299