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ADD3 Deletion in Glioblastoma Predicts Disease Status and Survival

Loss of heterozygosity (LOH) on chromosome 10 frequently occurs in gliomas. Whereas genetic loci with allelic deletion often implicate tumor suppressor genes, a putative tumor suppressor Adducin3 (ADD3) mapped to chromosome 10q25.2 was found to be preferentially downregulated in high-grade gliomas c...

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Detalles Bibliográficos
Autores principales: Kiang, Karrie Mei-Yee, Sun, Stella, Leung, Gilberto Ka-Kit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712675/
https://www.ncbi.nlm.nih.gov/pubmed/34970477
http://dx.doi.org/10.3389/fonc.2021.717793