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Adjunctive Probiotic Lactobacillus rhamnosus Probio-M9 Administration Enhances the Effect of Anti-PD-1 Antitumor Therapy via Restoring Antibiotic-Disrupted Gut Microbiota

Emerging evidence supports that the efficacy of immune checkpoint blockade (ICB) therapy is associated with the host’s gut microbiota, as prior antibiotic intake often leads to poor outcome and low responsiveness toward ICB treatment. Therefore, we hypothesized that the efficacy of ICB therapy like...

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Detalles Bibliográficos
Autores principales: Gao, Guangqi, Ma, Teng, Zhang, Tao, Jin, Hao, Li, Yalin, Kwok, Lai-Yu, Zhang, Heping, Sun, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712698/
https://www.ncbi.nlm.nih.gov/pubmed/34970262
http://dx.doi.org/10.3389/fimmu.2021.772532