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Alpha-2-Macroglobulin in Inflammation, Immunity and Infections

Alpha-2-macroglobulin is an extracellular macromolecule mainly known for its role as a broad-spectrum protease inhibitor. By presenting itself as an optimal substrate for endopeptidases of all catalytic types, alpha-2-macroglobulin lures active proteases into its molecular cage and subsequently ‘fla...

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Detalles Bibliográficos
Autores principales: Vandooren, Jennifer, Itoh, Yoshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712716/
https://www.ncbi.nlm.nih.gov/pubmed/34970276
http://dx.doi.org/10.3389/fimmu.2021.803244