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Glucocorticoids Promote Extracellular Matrix Component Remodeling by Activating YAP in Human Retinal Capillary Endothelial Cells

Remodeling of extracellular matrix (ECM) components of endothelial cells is the main cause of retinal vascular basement membrane (BM) thickening, which leads to the initiation and perpetuation of microvasculopathy of diabetic retinopathy (DR). Excessive amounts of glucocorticoids (GCs) are related t...

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Detalles Bibliográficos
Autores principales: Gu, Xianliang, Ge, Lingling, Ren, Bangqi, Fang, Yajie, Li, Yijian, Wang, Yi, Xu, Haiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712730/
https://www.ncbi.nlm.nih.gov/pubmed/34970541
http://dx.doi.org/10.3389/fcell.2021.738341