Treatment With Cladribine Selects IFNγ+IL17+ T Cells in RRMS Patients – An In Vitro Study

BACKGROUND: Multiple sclerosis (MS) is an incurable autoimmune disease mediated by a heterogeneous T cell population (CD3+CD161+CXCR3−CCR6+IFNγ−IL17+, CD3+CXCR3+CCR6+IFNγ+IL17+, and CD3+CXCR3+IFNγ+IL17− phenotypes) that infiltrates the central nervous system, eliciting local inflammation, demyelinat...

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Detalles Bibliográficos
Autores principales: Dobreanu, Minodora, Manu, Doina Ramona, Mănescu, Ion Bogdan, Gabor, Manuela Rozalia, Huţanu, Adina, Bărcuţean, Laura, Bălaşa, Rodica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712887/
https://www.ncbi.nlm.nih.gov/pubmed/34970256
http://dx.doi.org/10.3389/fimmu.2021.743010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712887/
https://www.ncbi.nlm.nih.gov/pubmed/34970256
http://dx.doi.org/10.3389/fimmu.2021.743010

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