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Bazedoxifene activates the angiotensin II-induced HUVEC hypertension model by targeting SIRT1

The shift in vascular function to vasoconstriction, pro-inflammatory state, oxidative stress and carbon monoxide deficiency may to endothelial dysfunction and injury, which is the key event in hypertension. Estrogen receptor modulators play a protective role in blood vessels. The present study aimed...

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Detalles Bibliográficos
Autores principales: Yu, Qian, Zhao, Jin, Liu, Baotang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713184/
https://www.ncbi.nlm.nih.gov/pubmed/34970343
http://dx.doi.org/10.3892/etm.2021.11043