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Synthesis and Cytotoxic Activity of Lepidilines A–D: Comparison with Some 4,5-Diphenyl Analogues and Related Imidazole-2-thiones

[Image: see text] A straightforward access to 2-unsubstituted imidazole N-oxides with subsequent deoxygenation by treatment with Raney-nickel followed by N-benzylation opens up a convenient route to lepidilines A and C. Both imidazolium salts were used to generate in situ the corresponding imidazol-...

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Detalles Bibliográficos
Autores principales: Mlostoń, Grzegorz, Kowalczyk, Mateusz, Celeda, Małgorzata, Gach-Janczak, Katarzyna, Janecka, Anna, Jasiński, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713287/
https://www.ncbi.nlm.nih.gov/pubmed/34808062
http://dx.doi.org/10.1021/acs.jnatprod.1c00797