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Natural rodent model of viral transmission reveals biological features of virus population dynamics

Emerging viruses threaten global health, but few experimental models can characterize the virus and host factors necessary for within- and cross-species transmission. Here, we leverage a model whereby pet store mice or rats—which harbor natural rodent pathogens—are cohoused with laboratory mice. Thi...

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Detalles Bibliográficos
Autores principales: Fay, Elizabeth J., Balla, Keir M., Roach, Shanley N., Shepherd, Frances K., Putri, Dira S., Wiggen, Talia D., Goldstein, Stephen A., Pierson, Mark J., Ferris, Martin T., Thefaine, Claire E., Tucker, Andrew, Salnikov, Mark, Cortez, Valerie, Compton, Susan R., Kotenko, Sergei V., Hunter, Ryan C., Masopust, David, Elde, Nels C., Langlois, Ryan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713297/
https://www.ncbi.nlm.nih.gov/pubmed/34958350
http://dx.doi.org/10.1084/jem.20211220