Transition from cMyc to L-Myc during dendritic cell development coordinated by rising levels of IRF8

During dendritic cell (DC) development, Myc expression in progenitors is replaced by Mycl in mature DCs, but when and how this transition occurs is unknown. We evaluated DC development using reporters for MYC, MYCL, and cell cycle proteins Geminin and CDT1 in wild-type and various mutant mice. For c...

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Detalles Bibliográficos
Autores principales: Anderson, David A., Ou, Feiya, Kim, Sunkyung, Murphy, Theresa L., Murphy, Kenneth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713298/
https://www.ncbi.nlm.nih.gov/pubmed/34958351
http://dx.doi.org/10.1084/jem.20211483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713298/
https://www.ncbi.nlm.nih.gov/pubmed/34958351
http://dx.doi.org/10.1084/jem.20211483

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