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MutL homolog 1 methylation and microsatellite instability in sporadic colorectal tumors among Filipinos
BACKGROUND: Colorectal cancer (CRC) ranks third in terms of incidence and second in mortality worldwide. In CRC, the silencing of mismatch repair genes, including the mutL homolog 1 (hMLH1) has been linked to microsatellite instability (MSI), the lengthening or shortening of microsatellite repeats....
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713326/ https://www.ncbi.nlm.nih.gov/pubmed/35070045 http://dx.doi.org/10.4251/wjgo.v13.i12.2101 |