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MutL homolog 1 methylation and microsatellite instability in sporadic colorectal tumors among Filipinos

BACKGROUND: Colorectal cancer (CRC) ranks third in terms of incidence and second in mortality worldwide. In CRC, the silencing of mismatch repair genes, including the mutL homolog 1 (hMLH1) has been linked to microsatellite instability (MSI), the lengthening or shortening of microsatellite repeats....

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Detalles Bibliográficos
Autores principales: Cabral, Loraine Kay D, Mapua, Cynthia A, Natividad, Filipinas F, Sukowati, Caecilia H C, Cortez, Edgardo R, Enriquez, Ma Luisa D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713326/
https://www.ncbi.nlm.nih.gov/pubmed/35070045
http://dx.doi.org/10.4251/wjgo.v13.i12.2101