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BRAF(V600E) mutant colorectal cancer cells mediate local immunosuppressive microenvironment through exosomal long noncoding RNAs

BACKGROUND: BRAF(V600E) mutated colorectal cancer (CRC) is prone to peritoneal and distant lymph node metastasis and this correlates with a poor prognosis. The BRAF(V600E )mutation is closely related to the formation of an immunosuppressive microenvironment. However, the correlation between BRAF(V60...

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Detalles Bibliográficos
Autores principales: Zhi, Jie, Jia, Xiao-Jing, Yan, Jing, Wang, Hui-Cong, Feng, Bo, Xing, Han-Ying, Jia, Yi-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713331/
https://www.ncbi.nlm.nih.gov/pubmed/35070047
http://dx.doi.org/10.4251/wjgo.v13.i12.2129