Insights Into the Inhibition of MOX-1 β-Lactamase by S02030, a Boronic Acid Transition State Inhibitor

The rise of multidrug resistant (MDR) Gram-negative bacteria has accelerated the development of novel inhibitors of class A and C β-lactamases. Presently, the search for novel compounds with new mechanisms of action is a clinical and scientific priority. To this end, we determined the 2.13-Å resolut...

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Detalles Bibliográficos
Autores principales: Ishikawa, Tatsuya, Furukawa, Nayuta, Caselli, Emilia, Prati, Fabio, Taracila, Magdalena A., Bethel, Christopher R., Ishii, Yoshikazu, Shimizu-Ibuka, Akiko, Bonomo, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713471/
https://www.ncbi.nlm.nih.gov/pubmed/34970229
http://dx.doi.org/10.3389/fmicb.2021.720036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713471/
https://www.ncbi.nlm.nih.gov/pubmed/34970229
http://dx.doi.org/10.3389/fmicb.2021.720036

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