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The HBV Core Protein and Core Particle Both Bind to the PPiase Par14 and Par17 to Enhance Their Stabilities and HBV Replication

We recently reported that the PPIase Par14 and Par17 encoded by PIN4 upregulate HBV replication in an HBx-dependent manner by binding to conserved arginine–proline (RP) motifs of HBx. HBV core protein (HBc) has a conserved (133)RP(134) motif; therefore, we investigated whether Par14/Par17 bind to HB...

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Detalles Bibliográficos
Autores principales: Saeed, Umar, Piracha, Zahra Zahid, Kwon, Hyeonjoong, Kim, Jumi, Kalsoom, Fadia, Chwae, Yong-Joon, Park, Sun, Shin, Ho-Joon, Lee, Hyun Woong, Lim, Jin Hong, Kim, Kyongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713550/
https://www.ncbi.nlm.nih.gov/pubmed/34970249
http://dx.doi.org/10.3389/fmicb.2021.795047