Systems biology analysis of human genomes points to key pathways conferring spina bifida risk

Spina bifida (SB) is a debilitating birth defect caused by multiple gene and environment interactions. Though SB shows non-Mendelian inheritance, genetic factors contribute to an estimated 70% of cases. Nevertheless, identifying human mutations conferring SB risk is challenging due to its relative r...

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Detalles Bibliográficos
Autores principales: Aguiar-Pulido, Vanessa, Wolujewicz, Paul, Martinez-Fundichely, Alexander, Elhaik, Eran, Thareja, Gaurav, Abdel Aleem, Alice, Chalhoub, Nader, Cuykendall, Tawny, Al-Zamer, Jamel, Lei, Yunping, El-Bashir, Haitham, Musser, James M., Al-Kaabi, Abdulla, Shaw, Gary M., Khurana, Ekta, Suhre, Karsten, Mason, Christopher E., Elemento, Olivier, Finnell, Richard H., Ross, M. Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713748/
https://www.ncbi.nlm.nih.gov/pubmed/34916285
http://dx.doi.org/10.1073/pnas.2106844118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713748/
https://www.ncbi.nlm.nih.gov/pubmed/34916285
http://dx.doi.org/10.1073/pnas.2106844118

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