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Constructing local cell-specific networks from single-cell data

Gene coexpression networks yield critical insights into biological processes, and single-cell RNA sequencing provides an opportunity to target inquiries at the cellular level. However, due to the sparsity and heterogeneity of transcript counts, it is challenging to construct accurate gene networks....

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Detalles Bibliográficos
Autores principales: Wang, Xuran, Choi, David, Roeder, Kathryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713783/
https://www.ncbi.nlm.nih.gov/pubmed/34903665
http://dx.doi.org/10.1073/pnas.2113178118