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Specific hypomethylation programs underpin B cell activation in early multiple sclerosis

Epigenetic changes have been consistently detected in different cell types in multiple sclerosis (MS). However, their contribution to MS pathogenesis remains poorly understood partly because of sample heterogeneity and limited coverage of array-based methods. To fill this gap, we conducted a compreh...

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Detalles Bibliográficos
Autores principales: Ma, Qin, Caillier, Stacy J., Muzic, Shaun, Wilson, Michael R., Henry, Roland G., Cree, Bruce A. C., Hauser, Stephen L., Didonna, Alessandro, Oksenberg, Jorge R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713784/
https://www.ncbi.nlm.nih.gov/pubmed/34911760
http://dx.doi.org/10.1073/pnas.2111920118