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A gene-centric approach to biomarker discovery identifies transglutaminase 1 as an epidermal autoantigen

Autoantigen discovery is a critical challenge for the understanding and diagnosis of autoimmune diseases. While autoantibody markers in current clinical use have been identified through studies focused on individual disorders, we postulated that a reverse approach starting with a putative autoantige...

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Detalles Bibliográficos
Autores principales: Landegren, Nils, Ishii, Norito, Aranda-Guillén, Maribel, Gunnarsson, Hörður Ingi, Sardh, Fabian, Hallgren, Åsa, Ståhle, Mona, Hagforsen, Eva, Bradley, Maria, Edqvist, Per-Henrik D., Pontén, Fredrik, Mäkitie, Outi, Eidsmo, Liv, Norlén, Lars, Achour, Adnane, Dahlbom, Ingrid, Korponay-Szabó, Ilma, Agardh, Daniel, Alimohammadi, Mohammad, Eriksson, Daniel, Hashimoto, Takashi, Kämpe, Olle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713791/
https://www.ncbi.nlm.nih.gov/pubmed/34911754
http://dx.doi.org/10.1073/pnas.2100687118