Genome instability drives epistatic adaptation in the human pathogen Leishmania

How genome instability is harnessed for fitness gain despite its potential deleterious effects is largely elusive. An ideal system to address this important open question is provided by the protozoan pathogen Leishmania, which exploits frequent variations in chromosome and gene copy number to regula...

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Detalles Bibliográficos
Autores principales: Bussotti, Giovanni, Piel, Laura, Pescher, Pascale, Domagalska, Malgorzata A., Rajan, K. Shanmugha, Cohen-Chalamish, Smadar, Doniger, Tirza, Hiregange, Disha-Gajanan, Myler, Peter J., Unger, Ron, Michaeli, Shulamit, Späth, Gerald F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713814/
https://www.ncbi.nlm.nih.gov/pubmed/34903666
http://dx.doi.org/10.1073/pnas.2113744118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713814/
https://www.ncbi.nlm.nih.gov/pubmed/34903666
http://dx.doi.org/10.1073/pnas.2113744118

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