Adult mouse and human organoids derived from thyroid follicular cells and modeling of Graves’ hyperthyroidism

The thyroid maintains systemic homeostasis by regulating serum thyroid hormone concentrations. Here we report the establishment of three-dimensional (3D) organoids from adult thyroid tissue representing murine and human thyroid follicular cells (TFCs). The TFC organoids (TFCOs) harbor the complete m...

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Detalles Bibliográficos
Autores principales: van der Vaart, Jelte, Bosmans, Lynn, Sijbesma, Stijn F., Knoops, Kèvin, van de Wetering, Willine J., Otten, Henny G., Begthel, Harry, Borel Rinkes, Inne H. M., Korving, Jeroen, Lentjes, Eef G. W. M., Lopez-Iglesias, Carmen, Peters, Peter J., van Santen, Hanneke M., Vriens, Menno R., Clevers, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713972/
https://www.ncbi.nlm.nih.gov/pubmed/34916298
http://dx.doi.org/10.1073/pnas.2117017118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713972/
https://www.ncbi.nlm.nih.gov/pubmed/34916298
http://dx.doi.org/10.1073/pnas.2117017118

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