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Biofidelic dynamic compression of human cortical spheroids reproduces neurotrauma phenotypes

Fundamental questions about patient heterogeneity and human-specific pathophysiology currently obstruct progress towards a therapy for traumatic brain injury (TBI). Human in vitro models have the potential to address these questions. Three-dimensional spheroidal cell culture protocols for human-orig...

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Detalles Bibliográficos
Autores principales: Shoemaker, Aaron R., Jones, Ian E., Jeffris, Kira D., Gabrielli, Gina, Togliatti, Alyssa G., Pichika, Rajeswari, Martin, Eric, Kiskinis, Evangelos, Franz, Colin K., Finan, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713991/
https://www.ncbi.nlm.nih.gov/pubmed/34746950
http://dx.doi.org/10.1242/dmm.048916